The SGCG Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to sarcoglycan gamma, and SGCG. This antibody recognizes Human antigen. The SGCG Antibody has been validated for the following applications: Immunohistochemistry.
Description
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C)